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EMD Millipore
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Phone: 800-645-5476
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20 June 2013
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Recombinant, truncated form of the v-Abl protein tyrosine kinase that contains the minimum region required for both kinase activity and fibroblast transformation expressed in E. coli. The catalytic domain of v-Abl is identical to that of c-Abl. Induces resistance to anti-cancer drugs by suppressing apoptosis, probably by upregulating Bcl-xL protein.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 100 mM NaCl, 50 mM HEPES, 1 mM DTT, 100 µM EDTA, 50% glycerol, 0.01% BRIJ® 35 Detergent, pH 7.5. | ||
| Molar mass | 45000 | ||
| Avoid freeze/thaw | Yes | ||
| Unit definition | One unit is defined as the amount of enzyme that will catalyze the transfer of 1.0 pmol phosphate to EAIYAAPFAKKK per min at 30°C, pH 7.5. | ||
| Activity | ≥100,000 units/ml | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
