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23 May 2013
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An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Mimics the effects of glycine on the NMDA receptor ion channel and blocks 3H-glycine binding to rat forebrain membrane (IC50 = 38 nM). Blocks NMDA-induced release of arachidonic acid (IC50 = 131 µM) in cerebellar granule cells. Reduces NMDA-induced cell death in hippocampal neurons.
| Product information | |||
|---|---|---|---|
| Form | Crystalline solid | ||
| Molar mass | 101.1 | ||
| Purity | ≥ 98% by TLC | ||
| Solubility | H2O | ||
| Chemical formula | C4H7NO2 | ||
| RTECS | GZ1110000 | ||
| CAS number | 22059-21-8 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Irritant |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
||
| R Phrase |
R: 36/37/38 Irritating to eyes, respiratory system and skin. |
||
