Parteck® MXP Excipient for Hot Melt Extrusion

 
 

Enhanced API Solubility and Stable, High Drug Loads


Poor solubility of APIs is a critical challenge in drug development. One formulation technique to address this challenge is hot melt extrusion (HME). Our new Parteck® MXP is a polyvinyl alcohol-based excipient designed for hot melt extrusion to increase solubility and allow for stable and high drug loads for a broad range of APIs. The polymer has a long safety record related to its usage in drugs and is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. Parteck® MXP complies with USP, Ph. Eur., and JPE monographs.

Benefits of Parteck® MXP:

  • Enhanced solubility of APIs
  • Stable, high drug load under various conditions
  • High thermo-stability (above 200 °C) and a Broad API Application Range
  • Variety of final oral dosage forms with immediate or sustained release kinetics using the same extrudates
  • Ease of use thanks to optimized physical properties
Cat. No.Product DescriptionQuantity
141464 Parteck® MXP (Polyvinyl alcohol) EMPROVE® ESSENTIAL Ph Eur,JPE,USP 1 kg, 25 kg

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Webinar: Hot Melt Extrusion with PVA: Overcoming Solubility and Bioavailability Challenges

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Hot Melt Extrusion with PVA: Overcoming Solubility and Bioavailability Challenges

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