High purity, low water content and customized solutions

DNA/RNA synthesis demands high-purity solvents with the lowest possible water content. MilliporeSigma provides a growing range of specialized solvents and reagents for DNA/RNA synthesis – both on a custom basis as well as for the broad market including core facilities and other commercial companies.

In addition to our high-purity dried acetonitrile for DNA synthesis, we offer activator solutions as well as capping, oxidation, and deblock reagents – all with the consistent quality and high purity you need for optimized yield and reliability. This is guaranteed by our state-of-the-art ISO 9001 quality management system and proven through a comprehensive Certificate of Analysis for each product.

Feature and Benefits

  • Comprehensive range of high-quality reagents
  • Lowest published specs for water and acid content and particulate levels
  • Broad range of packaging solutions for specific synthesis instrumentation
  • Quantities from bottle to bulk

Our solvents and reagents for DNA and RNA synthesis are specifically processed, purified and distilled to maximize synthesis efficiency and yields for these critical applications. They are available in a wide variety of packaging types including bottles of up to 4 liters. We also offer customized packaging, delivery, and engineering support that will allow you to make direct connections to your laboratory instruments.

As the field expands, we will continue to create new formulations, align with new synthesis instrumentation manufacturers, and broaden our DNA & RNA synthesis portfolio. So if you cannot find what you need, talk to us. We would be glad to work with you to develop new custom blended synthesis reagents and delivery mechanisms to meet your specific requirements.

Catalog Number Catalog Name
108218 Trifluoroacetic acid
108178 Trifluoroacetic acid
118605 Capping A
118608 Capping B
100574 1-Methyl-2-pyrrolidone
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Aug 26
08/26/18 - 08/30/18
TIAFT 2018
International Convention Centre (ICC)
Ghent, Belgium
Analytics and Sample Preparation Europe 20180826
Aug 27
08/27/18 - 08/31/18
EAFS 2018
Lyon Convention Center
Lyon, France
Analytics and Sample Preparation Europe 20180827