Why Test for Mycoplasmas in
Biopharmaceutical Manufacturing?


Mycoplasma contamination is a widespread and reoccurring problem in a wide variety of cell culture systems. These micro-organisms, which belong to the class Mollicutes, are comparatively small (0.2 – 0.3 µm), lack a cell wall and are thus not susceptible to penicillins or other antibiotics that act on this structure, and they show tolerance to many other antibiotics. This allows them to grow to high titers in culture media without exhibiting typical bacterial contamination signs, like turbidity.

Contamination of a bioreactor can lead to significant loss of time, materials and revenue unless identified early in the process. In fact, microbial contamination is one of the primary reasons for batch failure in biopharmaceutical production. It is therefore important to test for mycoplasmas at various points in the manufacturing process. To this end, EMD Millipore provides both compendial and rapid solutions for reliable Mycoplasma detection.

Mycoplasma Testing
 
 
Mycoplasma Culture Media Brochure

Brochure
Mycoplasma Culture Media

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MilliPROBE® System Brochure

Brochure
MilliPROBE® System

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Events

May 31
05/31/15 - 06/02/15
American Society for Microbiology (ASM)
New Orleans Ernest N. Morial Convention Center
New Orleans, LA, USA
,Reagents Chemicals and Labware,Life Science Research,Industrial Biomonitoring,IVD/OEM Materials and Reagents,Analytics and Sample Preparation North America 20150531
Jun 06
06/06/15 - 06/09/15
IACP Compounders on Capitol Hill
Renaissance Washington DC
Washington, DC, USA
Industrial Biomonitoring North America 20150606
Jun 09
06/09/15 - 06/10/15
PDA Aseptic Processing – Sterilization Conference
Loews Coronado Bay
San Diego, CA, USA
Industrial Biomonitoring,Biopharmaceutical Manufacturing North America 20150609
Jun 07
06/07/15 - 06/10/15
AWWA-ACE 15
Anaheim Convention Center
Anaheim, CA, USA
Reagents Chemicals and Labware,Analytics and Sample Preparation North America 20150607
Jun 10
06/10/15 - 06/12/15
55° SIMPOSIO AFI
Palacongressi Della Riviera | Ingresso B | Via della Fiera, 23
Rimini (Italia), Italy
,Small Molecule Pharmaceuticals,Reagents Chemicals and Labware,Life Science Research,Industrial Biomonitoring,IVD/OEM Materials and Reagents,Biopharmaceutical Manufacturing,Analytics and Sample Preparation Europe 20150610