506126 | p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem

506126
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₁₃ClFN₃O 219138-24-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      506126-500UG
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          Plastic ampoule 500 μg
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          Description
          OverviewA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
          Catalogue Number506126
          Brand Family Calbiochem®
          Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
          References
          Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.
          Product Information
          CAS number219138-24-6
          ATP CompetitiveN
          FormPale yellow solid
          Hill FormulaC₂₀H₁₃ClFN₃O
          Chemical formulaC₂₀H₁₃ClFN₃O
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetp38 MAP kinase
          Primary Target IC<sub>50</sub>35 nM
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          506126

          References

          Reference overview
          de Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.

          Brochure

          Title
          DNA Repair Pathway Poster
          MAP Kinases Technical Bulletin
          MAPK Pathway Poster ( 750 KB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-October-2007 JSW
          Synonyms2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
          DescriptionA potent p38 MAP kinase inhibitor (IC50 = 35 nM).
          FormPale yellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number219138-24-6
          Chemical formulaC₂₀H₁₃ClFN₃O
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (25 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          Referencesde Laszlo, S.E., et al. 1998. Bioorg. Med. Chem. Lett. 8, 2689.