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508508 | Zonisamide - CAS 68291-97-4 - Calbiochem

508508
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₈N₂O₃S 68291-97-4

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.08508.0001
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          Glass bottle 10 mg
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          Description
          OverviewA benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number508508
          Brand Family Calbiochem®
          SynonymsAD 810, CI 912
          References
          ReferencesSonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
          Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.
          Product Information
          CAS number 68291-97-4
          FormWhite solid
          Hill FormulaC₈H₈N₂O₃S
          Chemical formulaC₈H₈N₂O₃S
          Structure formula Image
          Applications
          Biological Information
          Primary TargetNa+ and Ca2+ channels
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 22

          Harmful if swallowed.
          S PhraseS: 36/37/39-45-46

          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          If swallowed, seek medical advice immediately and show this container or label.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Harmful
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Sonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
          Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision31-January-2014 JSW
          SynonymsAD 810, CI 912
          DescriptionA benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.
          FormWhite solid
          CAS number 68291-97-4
          Chemical formulaC₈H₈N₂O₃S
          Structure formula
          Purity≥98% by HPLC
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Toxicity Harmful
          ReferencesSonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
          Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.