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505816 | Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem

505816
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₂₃N₃OS•C₂H₂O₄ 141064-23-5

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05816.0001
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          Glass bottle 10 mg
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          Description
          OverviewAn agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
          Catalogue Number505816
          Brand Family Calbiochem®
          Synonyms3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
          References
          ReferencesWang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
          Si, W., et al., 2010. Neurosci. Lett. 473, 115.
          Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.
          Product Information
          CAS number141064-23-5
          FormOff-white solid
          Hill FormulaC₁₄H₂₃N₃OS•C₂H₂O₄
          Chemical formulaC₁₄H₂₃N₃OS•C₂H₂O₄
          Structure formula Image
          Applications
          Biological Information
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Wang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
          Si, W., et al., 2010. Neurosci. Lett. 473, 115.
          Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          Synonyms3-(hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole, Muscarinic Acetylcholine Receptor (mAChR) Agonist, Xanomeline
          DescriptionAn agonist selective for muscarinic acetylcholine receptor (mAChR) subtype M1 (EC50 = 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). An antipsychotic agent. Used in improving cognitive deficits and behavioral disturbances in Alzheimer′s disease and schizophrenia.
          FormOff-white solid
          CAS number141064-23-5
          Chemical formulaC₁₄H₂₃N₃OS•C₂H₂O₄
          Structure formula
          Purity≥99% by HPLC
          SolubilityDMSO (10 mM) or Ethanol (25 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesWang, D., et al., 2011. Biochem. Biophys. Res. Commun. 410, 229.
          Si, W., et al., 2010. Neurosci. Lett. 473, 115.
          Stanhope, et al., 2001. J. Exp. Pharmacol. Ther. 299, 782.