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Description
Overview
A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22. Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026. Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.
Product Information
CAS number
99300-78-4
Form
White solid
Hill Formula
C₁₇H₂₇NO₂·HCl
Chemical formula
C₁₇H₂₇NO₂·HCl
Structure formula Image
Applications
Biological Information
Primary Target
SERT/NET
Primary Target K<sub>i</sub>
82 nM
Purity
≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Standard Handling
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas
Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Documentation
Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem SDS
Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22. Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026. Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
Form
White solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
99300-78-4
Chemical formula
C₁₇H₂₇NO₂·HCl
Structure formula
Purity
≥99% by HPLC
Solubility
DMSO (50 mM) or H₂O (100 mM)
Storage
+2°C to +8°C
Protect from light
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22. Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026. Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.