506135 Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien

Primary Target: SERT/NET
506135
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₇H₂₇NO₂·HCl 99300-78-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.06135.0001
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          		 Glass bottle 10 mg
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          Description
          OverviewA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
          Catalogue Number506135
          Brand Family Calbiochem®
          SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
          References
          ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
          Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
          Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
          Product Information
          CAS number99300-78-4
          FormWhite solid
          Hill FormulaC₁₇H₂₇NO₂·HCl
          Chemical formulaC₁₇H₂₇NO₂·HCl
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetSERT/NET
          Primary Target K<sub>i</sub>82 nM
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
          Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
          Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision15-November-2013 JSW
          SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
          DescriptionA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number99300-78-4
          Chemical formulaC₁₇H₂₇NO₂·HCl
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (50 mM) or H₂O (100 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
          Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
          Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.