676473 VEGF₁₂₁, Human, Recombinant, S. frugiperda

676473
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      Overview

      Replacement Information

      Key Specifications Table

      Purity
      ≥90% by SDS-PAGE

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      676473-5UG
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      Stocked 
      Discontinued
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      Available
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          Plastic ampoule 5 μg
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          Description
          OverviewRecombinant, human VEGF121 (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF121 is dominantly expressed in most tumor cell lines. Forms a biologically active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.
          Catalogue Number676473
          Brand Family Calbiochem®
          SynonymsVascular Endothelial Growth Factor₁₂₁
          References
          ReferencesStimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
          Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
          Wilting, J., et al. 1996. Dev. Biol. 176, 76.
          Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.
          Product Information
          FormLyophilized
          Applications
          Biological Information
          Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
          Purity≥90% by SDS-PAGE
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze at -70°C. Stock solutions are stable for up to 3 months at -70°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          VEGF₁₂₁, Human, Recombinant, S. frugiperda SDS

          Title

          Safety Data Sheet (SDS) 

          VEGF₁₂₁, Human, Recombinant, S. frugiperda Certificates of Analysis

          TitleLot Number
          676473

          References

          Reference overview
          Stimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
          Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
          Wilting, J., et al. 1996. Dev. Biol. 176, 76.
          Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-February-2019 JSW
          SynonymsVascular Endothelial Growth Factor₁₂₁
          DescriptionRecombinant, human VEGF121 (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF121 is dominantly expressed in most tumor cell lines. Forms a biological active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.
          FormLyophilized
          Purity≥90% by SDS-PAGE
          Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
          Solubility0.1 M acetic acid or H₂O.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze at -70°C. Stock solutions are stable for up to 3 months at -70°C.
          Toxicity Standard Handling
          ReferencesStimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
          Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
          Wilting, J., et al. 1996. Dev. Biol. 176, 76.
          Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.