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662091 | Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli

662091
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      662091-50UG
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
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      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Glass bottle 50 μg
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          Description
          OverviewRecombinant, human ubiquitin conjugating enzyme 5a fused to GST and expressed in E. coli. E2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family which has been shown to play many important regulatory roles in inflammation and cancer.
          Catalogue Number662091
          Brand Family Calbiochem®
          SynonymsGST-Ubc5a (E2)
          References
          ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
          Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
          Ciechanover, A. 1994. Cell 79, 13.
          Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
          Product Information
          FormLiquid
          FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
          Applications
          Biological Information
          Purity≥95% by SDS-PAGE
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          662091

          References

          Reference overview
          Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
          Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
          Ciechanover, A. 1994. Cell 79, 13.
          Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.

          Citations

          Title
        • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision16-September-2008 RFH
          SynonymsGST-Ubc5a (E2)
          DescriptionE2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family that has been shown to play many important regulatory roles in inflammation and cancer.
          FormLiquid
          FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
          Concentration Label Please refer to vial label for lot-specific concentration
          Purity≥95% by SDS-PAGE
          Storage ≤ -70°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
          Toxicity Standard Handling
          ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
          Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
          Ciechanover, A. 1994. Cell 79, 13.
          Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
          Citation
        • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.