625625 Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem

625625
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₂H₂₂O₁₁ · 2H₂O 6138-23-4

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      625625-1KG
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          Glass bottle 1 kg
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          625625-50GM
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              Glass bottle 50 gm
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              Description
              OverviewNon-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
              Catalogue Number625625
              Brand Family Calbiochem®
              Synonyms1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
              References
              ReferencesSarkar, S., et al. 2007. J. Biol. Chem. In press.
              Tanaka, M., et al. 2004. Nat. Med. 10, 148.
              Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.
              Product Information
              CAS number6138-23-4
              FormSolid
              Hill FormulaC₁₂H₂₂O₁₁ · 2H₂O
              Chemical formulaC₁₂H₂₂O₁₁ · 2H₂O
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Purity≥97.5% by Assay
              Physicochemical Information
              ContaminantsHeavy metals: <10 ppm; iron: <5 ppm
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              S PhraseS: 24/25-37-45

              Avoid contact with skin and eyes.
              Wear suitable gloves.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +15°C to +30°C
              Do not freeze Ok to freeze
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem Certificates of Analysis

              TitleLot Number
              625625

              References

              Reference overview
              Sarkar, S., et al. 2007. J. Biol. Chem. In press.
              Tanaka, M., et al. 2004. Nat. Med. 10, 148.
              Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.

              Brochure

              Title
              Bulk packaging
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision30-April-2010 JSW
              Synonyms1-O-α-D-Glucopyranosyl-α-D-glucopyranoside
              DescriptionNon-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
              FormSolid
              CAS number6138-23-4
              Chemical formulaC₁₂H₂₂O₁₁ · 2H₂O
              Structure formulaStructure formula
              Purity≥97.5% by Assay
              ContaminantsHeavy metals: <10 ppm; iron: <5 ppm
              SolubilityH₂O (100 mg/ml)
              Storage +15°C to +30°C
              Do Not Freeze Ok to freeze
              Toxicity Standard Handling
              Merck USA index14, 9580
              ReferencesSarkar, S., et al. 2007. J. Biol. Chem. In press.
              Tanaka, M., et al. 2004. Nat. Med. 10, 148.
              Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.