614350 Tomatidine, HCl - CAS 6192-62-7 - Calbiochem

614350
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₇H₄₅NO₂ • HCl 6192-62-7

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      614350-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewA steroidal alkaloid that structurally resembles Cyclopamine (Cat. No. 239803), but lacks the capacity to inhibit Shh (Sonic Hedgehog) signaling. Reported to be non-teratogenic.
          Catalogue Number614350
          Brand Family Calbiochem®
          References
          ReferencesBerman, D.M., et al. 2003. Nature, 425, 846.
          Thayer, S.P., et al. 2003. Nature, 425, 851.
          Watkins, D.N., et al. 2003. Nature 422, 313.
          Cooper, M.K., et al. 1998. Science 280, 1603.
          Kim, S.K. and Melton, D.A. 1998. Proc. Natl. Acad. Sci. USA 95, 13036.
          Product Information
          CAS number6192-62-7
          ATP CompetitiveN
          FormOff-white solid
          Hill FormulaC₂₇H₄₅NO₂ • HCl
          Chemical formulaC₂₇H₄₅NO₂ • HCl
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetNegative control for Shh (Sonic Hedgehog) signaling
          Purity≥90% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Tomatidine, HCl - CAS 6192-62-7 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Tomatidine, HCl - CAS 6192-62-7 - Calbiochem Certificates of Analysis

          TitleLot Number
          614350

          References

          Reference overview
          Berman, D.M., et al. 2003. Nature, 425, 846.
          Thayer, S.P., et al. 2003. Nature, 425, 851.
          Watkins, D.N., et al. 2003. Nature 422, 313.
          Cooper, M.K., et al. 1998. Science 280, 1603.
          Kim, S.K. and Melton, D.A. 1998. Proc. Natl. Acad. Sci. USA 95, 13036.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2008 RFH
          DescriptionA steroidal alkaloid that structurally resembles Cyclopamine (Cat. No. 239803), but lacks the capacity to inhibit Sonic Hedgehog (Shh) signaling. Reported to be non-teratogenic. Useful as a negative control.
          FormOff-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number6192-62-7
          Chemical formulaC₂₇H₄₅NO₂ • HCl
          Structure formulaStructure formula
          Purity≥90% by TLC
          SolubilityDMSO (2 mg/ml), Ethanol (2.5 mg/ml), DMF (2 mg/ml), or Methanol:Chloroform (1:1, 50 mg/ml). Slight warming may be required to achieve complete solubilization.
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBerman, D.M., et al. 2003. Nature, 425, 846.
          Thayer, S.P., et al. 2003. Nature, 425, 851.
          Watkins, D.N., et al. 2003. Nature 422, 313.
          Cooper, M.K., et al. 1998. Science 280, 1603.
          Kim, S.K. and Melton, D.A. 1998. Proc. Natl. Acad. Sci. USA 95, 13036.