582235 Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem

582235
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      582235-10UG
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          Alu drum 10 μg
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          Description
          OverviewThe C-terminal binding portion of the heavy chain of tetanus toxin. Useful for binding studies.
          Caution: may contain trace amounts of intact toxin.
          Catalogue Number582235
          Brand Family Calbiochem®
          SynonymsTsTx-KαTTC
          References
          ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
          Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
          Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
          Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
          Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
          ReversibleN
          Applications
          Biological Information
          Primary TargetUseful for binding studies
          PuritySingle major band by SDS-PAGE
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 26/27/28

          Very toxic by inhalation, in contact with skin and if swallowed.
          S PhraseS: 45

          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
          Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem Certificates of Analysis

          TitleLot Number
          582235

          References

          Reference overview
          Poulain, B. 1994. Pathol. Biol. 42, 173.
          Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
          Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
          Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
          Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-September-2007 RFH
          SynonymsTsTx-KαTTC
          DescriptionThe C-terminal binding portion of the chain of tetanus toxin. The intact toxin is known to block neurotransmitter release at inhibitory synapses in cultured spinal cord cells. Shows trans-synaptic retrograde transport in the central nervous system. Caution: may contain trace amounts of intact toxin. Follow the handling procedure described in the information that accompanies the product.
          FormLyophilized
          FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
          PuritySingle major band by SDS-PAGE
          SolubilitySterile distilled H₂O
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
          Toxicity Highly Toxic
          ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
          Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
          Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
          Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
          Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.