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14-739 | TLK2 Protein, active, 10 µg

10 µg  Also available in 250μg size as catalog # 14-739M - Call for pricing and availability.
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      Replacement Information
      Catalogue Number14-739
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionTLK2 Protein, active, 10 µg
      OverviewN-terminal 6His-tagged, recombinant, 388-end, human TLK2.
      Alternate Names
      • tousled-like kinase 2
      Product Information
      ApplicationActive, N-terminal 6His-tagged, recombinant, 388-end, human TLK2. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThe Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM]
      Gene Symbol
      • TLK2
      • MGC44450
      • PKU-alpha
      • PKU-ALPHA
      Protein TargetTLK2
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyMisc
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q86UE8 # Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
      COFACTOR: Magnesium.
      SIZE: 772 amino acids; 87661 Da
      SUBUNIT: Heterodimerizes with TLK1. Interacts with ASF1A and ASF1B.
      TISSUE SPECIFICITY: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
      SIMILARITY: SwissProt: Q86UE8 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight48.8 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.
      Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250μg size as catalog # 14-739M - Call for pricing and availability.
      Transport Information
      Supplemental Information

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-739M TLK2 Protein, active, 250 µg Show Pricing & Availability


      Catalog Number Description  
      20-109 Protein Dilution Buffer B+ Show Pricing & Availability

      Product Families


      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases