581500 TEMPOL - CAS 2226-96-2 - Calbiochem

581500
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₉H₁₈NO₂ 2226-96-2

      Pricing & Availability

      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      581500-500MG
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          Plastic ampoule 500 mg
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          Description
          OverviewA stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
          Catalogue Number581500
          Brand Family Calbiochem®
          Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
          References
          ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
          Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
          Mota-Filipe, H., et al. 1999. Shock 12, 255.
          Product Information
          CAS number2226-96-2
          ATP CompetitiveN
          FormOrange powder or crystals
          Hill FormulaC₉H₁₈NO₂
          Chemical formulaC₉H₁₈NO₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetFree radical scavenger and nitric oxide spin trap
          Purity≥97% by nitrogen content
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSTN8991000
          Safety Information
          R PhraseR: 22-41

          Harmful if swallowed.
          Risk of serious damage to eyes.
          S PhraseS: 39-26

          Wear eye/face protection.
          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          TEMPOL - CAS 2226-96-2 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          TEMPOL - CAS 2226-96-2 - Calbiochem Certificates of Analysis

          TitleLot Number
          581500

          References

          Reference overview
          Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
          Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
          Mota-Filipe, H., et al. 1999. Shock 12, 255.

          Brochure

          Title
          Pathways and Biomarkers of Oxidative Stress (EMD)
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-June-2018 JSW
          Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
          DescriptionA stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
          FormOrange powder or crystals
          Intert gas (Yes/No) Packaged under inert gas
          CAS number2226-96-2
          RTECSTN8991000
          Chemical formulaC₉H₁₈NO₂
          Structure formulaStructure formula
          Purity≥97% by nitrogen content
          SolubilityDMSO (5 mg/ml), ethanol, or H₂O
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
          Toxicity Harmful
          ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
          Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
          Mota-Filipe, H., et al. 1999. Shock 12, 255.