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03-0072-00 | Singulex Erenna SMC Interleukin 1 alpha (IL-1α)
VERIFIED IMMUNOASSAY KIT

03-0072-00
96-well strip plate  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey Applications
      H Single Molecule Counting
      Description
      Catalogue Number03-0072-00
      Trade Name
      • Singulex
      DescriptionSingulex Erenna SMC Interleukin 1 alpha (IL-1α)
      VERIFIED IMMUNOASSAY KIT
      OverviewThe Singulex® Erenna® SMC® IL-1α Immunoassay Kit contains all reagents required to perform assays on the Erenna® Immunoassay System. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The Erenna® Immunoassay System detects analytes using Single Molecule Counting (SMC®) technology.
      Background InformationInterleukin-1 alpha and beta (IL-1α and IL-1β) are pro-inflammatory cytokines involved in immune defense against infection, and are part of the IL-1 superfamily of cytokines. Both IL-1α and IL-1β are produced by macrophages, monocytes and dendritic cells. IL-1 is involved in various immune responses with a primary role in inflammation, making it a target for Rheumatoid Arthritis (RA). IL-1α and IL-1β are produced as precursor peptides, which are proteolytically processed and released in response to cell injury, and thus induce apoptosis. IL-1β production in peripheral tissue has also been associated with hyperalgesia (increased sensitivity to pain) associated with fever.
      References
      Product Information
      Components
      • IL-1α Coated Beads
      • Standard Diluent
      • IL-1α Detection Antibody
      • Assay Buffer
      • IL-1α Standard
      • Erenna IL-1α Immunoassay Kit Instructions
      • 10X Wash Buffer
      • Elution Buffer B
      • Buffer D
      Precision, %
      • Low-end CV% Range: 2 - 19%
      • Low-end CV% Average: 7%
      Applications
      ApplicationThe sensitivity of the Single Molecule Counting (SMC) from Singulex gives the Erenna Human IL-1α Immunoassay Kit unparalleled performance in the quantification of IL-1α in human EDTA plasma.
      Key Applications
      • Single Molecule Counting
      Biological Information
      Species Reactivity
      • Human
      Accuracy
      • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
      Physicochemical Information
      Linearity of DilutionMinimum of 10 samples spiked and diluted (at least 3 dilutions) with acceptable recovery between 80-120%.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Erenna SMC™ IL-1 α Immunoassay Kit Instructions

      Brochure

      Title
      A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions.
      Protein Detection Platform and Services Brochure
      Singulex Erenna® Immunoassay System (EMD)

      Technical Info

      Title
      96 well Template 2 Up
      96 well Template Single
      Singulex Erenna® single molecule counting immunoassays outperform electrochemiluminescence (ECL) methods (EMD)

      Posters

      Title
      Multiplex Assays of Fifteen Human Complement Factors

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      Categories

      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits