A part of MilliporeSigma

505723 | SCH 23390 Hydrochloride - CAS 125941-87-9 - Calbiochem

505723
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₇H₁₈ClNO•HCl 125941-87-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05723.0001
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Glass bottle 10 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively).
          Catalogue Number505723
          Brand Family Calbiochem®
          SynonymsDopamine Receptor D1/D5 Antagonist, SCH 23390, (R)-(+)-7-Chloro-8-hydroxy-3-methyl­-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride, SCH23390, SCH-23390
          References
          ReferencesSplinter, M. Y. 2007. Ann. Pharmacother. 41, 285.
          Pfeiffer, R. F. 2002. Drugs Aging. 19, 561.
          Product Information
          CAS number125941-87-9
          FormOff-white solid
          Hill FormulaC₁₇H₁₈ClNO•HCl
          Chemical formulaC₁₇H₁₈ClNO•HCl
          Structure formula Image
          Applications
          Biological Information
          Primary TargetD1 and D5
          Primary Target K<sub>i</sub>0.2 nM
          Purity≥99% by Chiral HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Splinter, M. Y. 2007. Ann. Pharmacother. 41, 285.
          Pfeiffer, R. F. 2002. Drugs Aging. 19, 561.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-August-2013 JSW
          SynonymsDopamine Receptor D1/D5 Antagonist, SCH 23390, (R)-(+)-7-Chloro-8-hydroxy-3-methyl­-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride, SCH23390, SCH-23390
          DescriptionA highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively).
          FormOff-white solid
          CAS number125941-87-9
          Chemical formulaC₁₇H₁₈ClNO•HCl
          Structure formula
          Purity≥99% by Chiral HPLC
          SolubilityH₂O (100 mM)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSplinter, M. Y. 2007. Ann. Pharmacother. 41, 285.
          Pfeiffer, R. F. 2002. Drugs Aging. 19, 561.