505877 (S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem

505877
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₅H₂₀Cl₂N₂O₃ 84225-95-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05877.0001
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Glass bottle 10 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
          Catalogue Number505877
          Brand Family Calbiochem®
          SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
          References
          ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
          Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
          Product Information
          CAS number84225-95-6
          FormOff-white solid
          Hill FormulaC₁₅H₂₀Cl₂N₂O₃
          Chemical formulaC₁₅H₂₀Cl₂N₂O₃
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetD₂
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Dang, Y. H. et al. 2010. Neurosci. 169, 1872.
          Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
          DescriptionD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
          FormOff-white solid
          CAS number84225-95-6
          Chemical formulaC₁₅H₂₀Cl₂N₂O₃
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (100 mM) or Ethanol (25 mM)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
          Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.