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505228 | S 24795 - CAS 304679-75-2 - Calbiochem

505228
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₁₃BrNOI 304679-75-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05228.0001
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          Glass bottle 10 mg
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          Description
          OverviewA potent partial agonist selective for α7 nAChRs (EC50 = 34 µM). Widely used in investigating the roles of α7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer′s disease.
          Catalogue Number505228
          Brand Family Calbiochem®
          Synonyms2-(2-(4-bromophenyl)-2-oxoethyl)-1-methylpyridin-1-ium iodide, alpha 7 nAChR agonist, S 24795, S-24795, S24795, alpha 7 Nicotinic Acetylcholine Receptor Agonist, S 24795
          References
          ReferencesTronche, C., et al., 2010. Behav Brain Res. 215, 255.
          Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
          Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
          Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.
          Product Information
          CAS number304679-75-2
          FormPink solid
          Hill FormulaC₁₄H₁₃BrNOI
          Chemical formulaC₁₄H₁₃BrNOI
          Structure formula Image
          Applications
          Biological Information
          Primary Target→7 nAChRs
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Tronche, C., et al., 2010. Behav Brain Res. 215, 255.
          Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
          Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
          Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-July-2013 JSW
          Synonyms2-(2-(4-bromophenyl)-2-oxoethyl)-1-methylpyridin-1-ium iodide, alpha 7 nAChR agonist, S 24795, S-24795, S24795, alpha 7 Nicotinic Acetylcholine Receptor Agonist, S 24795
          DescriptionA potent partial agonist selective for α7 nAChRs (EC50 = 34 µM). Widely used in investigating the roles of α7 nAChRs in aging, learning and memory, and cognition. Enhances memory in mouse models for Alzheimer′s disease.
          FormPink solid
          CAS number304679-75-2
          Chemical formulaC₁₄H₁₃BrNOI
          Structure formula
          Purity≥99% by HPLC
          SolubilityDMSO (100 mM)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesTronche, C., et al., 2010. Behav Brain Res. 215, 255.
          Beracochea, D., et al., 2008. Psychopharmacol. (Berl). 196, 555.
          Lagostena, L., et al., 2008. Neuropharmacol. 54, 676.
          Lopez-Hernandez, G., et al., 2007. Neuropharmacol. 53, 134.