505881 | (R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem

505881
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C16H₁₇NO₂•HCl 81702-42-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05881.0001
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          Glass bottle 5 mg
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          Description
          OverviewA benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects.
          Catalogue Number505881
          Brand Family Calbiochem®
          SynonymsDopamine D₁/D₅ Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393
          References
          ReferencesTrampus, M. et al. 1993. J. Pharmacol. 235, 83.
          Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
          Dubois, A. et al. 1986. Neurosci. 19, 125.
          Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.
          Product Information
          CAS number81702-42-3
          FormWhite solid
          Hill FormulaC16H₁₇NO₂•HCl
          Chemical formulaC16H₁₇NO₂•HCl
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetD₁
          Purity≥98% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Trampus, M. et al. 1993. J. Pharmacol. 235, 83.
          Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
          Dubois, A. et al. 1986. Neurosci. 19, 125.
          Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          SynonymsDopamine D₁/D₅ Receptor Partial Agonist, (R)-SKF-38393 Hydrochloride, SKF-38393, SKF38393, SKF 38393
          DescriptionA benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects.
          FormWhite solid
          CAS number81702-42-3
          Chemical formulaC16H₁₇NO₂•HCl
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (100 mM)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesTrampus, M. et al. 1993. J. Pharmacol. 235, 83.
          Cooper, S. J. et al. 1990. Psychopharmacol. 100, 182.
          Dubois, A. et al. 1986. Neurosci. 19, 125.
          Kaiser, C. C. et al. 1982. J. Med. Chem. 25, 697.