526511 Phytohemagglutinin-M, Phaseolus vulgaris

526511
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      Overview

      Replacement Information

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      526511-20MG
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          Glass bottle 20 mg
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          Description
          OverviewStimulates the proliferation of human lymphocytes and mouse splenic T cells. Causes agglutination titers of 1:128 in tests using 2% solution of type A red blood cells.
          Catalogue Number526511
          Brand Family Calbiochem®
          References
          ReferencesDupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
          Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.
          Product Information
          CAS number9008-97-3
          FormLyophilized
          Applications
          Biological Information
          Biological activityOptimum activity for the stimulation of proliferation of lymphocytes is at 5-10 µg/ml.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSTJ3470000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          526511

          References

          Reference overview
          Dupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
          Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-May-2018 JSW
          DescriptionT-cell mitogen that stimulates the proliferation of human lymphocytes and mouse splenic T-cells. PHA is a mixture of tetramers consisting of combinations of two subunits, E and L, with different biological activity. E-4 isolectin has low mitogenic activity and high erythroagglutinating activity. L-4 isolectin has high mitogenic and leukoagglutinating activities and low erythroagglutinating activity. Causes agglutination titers of 1:128 in tests that use a 2% solution of type A red blood cells. Inhibited by N-acetyl-D-galactosamine, peptides containing the sequence NANA-D-Gal-(1 → 3,4), GlcNAcα(1 → 2), or Man α(1 → 2)Man.
          FormLyophilized
          CAS number9008-97-3
          RTECSTJ3470000
          Biological activityOptimum activity for the stimulation of proliferation of lymphocytes is at 5-10 µg/ml.
          SolubilitySterile redistilled H₂O (2-10 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Toxicity Standard Handling
          Merck USA index14, 5429
          ReferencesDupis, G., and Leclair, B. 1982. FEBS Lett. 144, 29.
          Felsted, R.L., et al. 1977. J. Biol. Chem. 252, 2967.