506125 | Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem

506125
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₉H₂₀FNO₃·HCl 110429-35-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.06125.0001
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          Glass bottle 10 mg
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          Description
          OverviewA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
          Catalogue Number506125
          Brand Family Calbiochem®
          Synonyms5-HT transporter, Paroxetine, Paxil
          References
          ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
          Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
          Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
          Product Information
          CAS number110429-35-1
          FormWhite solid
          Hill FormulaC₁₉H₂₀FNO₃·HCl
          Chemical formulaC₁₉H₂₀FNO₃·HCl
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Target5-HT Uptake Transporter
          Primary Target K<sub>i</sub>0.065 nM
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
          Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
          Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-September-2013 JSW
          Synonyms5-HT transporter, Paroxetine, Paxil
          DescriptionA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number110429-35-1
          Chemical formulaC₁₉H₂₀FNO₃·HCl
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
          Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
          Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.