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14-677 | PRKX Protein, active, 10 µg

10 µg  
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      Replacement Information
      Catalogue Number14-677
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPRKX Protein, active, 10 µg
      OverviewN-terminal 6His-tagged, recombinant, full length, human PRKX
      Product Information
      ApplicationActive, N-terminal 6His-tagged, recombinant, full length, human PRKX, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • PRKX
      • PKX1
      Protein TargetPrKX
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummarySIZE: 358 amino acids; 40896 Da
      TISSUE SPECIFICITY: High levels in adult and fetal brain, kidney and lung; low levels in adult placenta, heart, liver, skeletal muscle, pancreas and fetal liver.
      DISEASE: SwissProt: P51817 # A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.
      SIMILARITY: SwissProt: P51817 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.
      Molecular Weight44.7kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of PAKtide
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      PrKX, active - 1663805 1663805
      PrKX, active - 32835U-A 32835U-A
      PrKX, active - 32835U-B 32835U-B
      PrKX, active - 32835U-C 32835U-C


      Reference overviewPub Med ID
      PKA/PrKX activity is a modulator of AAV/adenovirus interaction.
      Di Pasquale, Giovanni and Chiorini, John A
      EMBO J., 22: 1716-24 (2003) 2003

      Show Abstract
      12660177 12660177
      PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis.
      Li, Xiaohong, et al.
      Proc. Natl. Acad. Sci. U.S.A., 99: 9260-5 (2002) 2002

      Show Abstract
      12082174 12082174

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      Product Families


      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases