516566 | PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem

516566
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₆H₁₉N₃O₅ 36099-95-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      516566-50MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Plastic ampoule 50 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
          Catalogue Number516566
          Brand Family Calbiochem®
          SynonymsH-Trp-Glu-OH
          References
          ReferencesYe, F., et al. 2006. Chembiochem 7, 74.
          Product Information
          CAS number36099-95-3
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₆H₁₉N₃O₅
          Chemical formulaC₁₆H₁₉N₃O₅
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPPARγ
          Primary Target IC<sub>50</sub>kd = ~ 8 µM as PPARγ antagonist
          Purity≥97% by elemental analysis
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          516566

          References

          Reference overview
          Ye, F., et al. 2006. Chembiochem 7, 74.

          Brochure

          Title
          Biologics 32.4 ( 1.19 MB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-October-2007 RFH
          SynonymsH-Trp-Glu-OH
          DescriptionA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number36099-95-3
          Chemical formulaC₁₆H₁₉N₃O₅
          Structure formulaStructure formula
          Purity≥97% by elemental analysis
          SolubilityH₂O (30 mg/ml). Addition of a small amount of acid or base may be required for complete solubilization.
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesYe, F., et al. 2006. Chembiochem 7, 74.