505761 | PPADS

505761
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₄H₁₀N₃Na₄O₁₂PS₂ 192575-19-2

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05761.0001
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          Glass bottle 10 mg
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          Description
          OverviewA selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.

          Please note that the molecular weight for this compound is batch-specific due to variable water content.
          Catalogue Number505761
          Brand Family Calbiochem®
          SynonymsP2 Purinergic Receptor Antagonist, PPADS
          References
          ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
          Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
          Product Information
          CAS number192575-19-2
          FormOrange solid
          Hill FormulaC₁₄H₁₀N₃Na₄O₁₂PS₂
          Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Target IC<sub>50</sub>2.5 µ
          Purity≥90 by 1H NMR
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Li. C. 2000. J. Neurophysiol. 83, 2533.
          Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision04-April-2014 JSW
          SynonymsP2 Purinergic Receptor Antagonist, PPADS
          DescriptionA selective P2 purinergic receptor antagonist that block ATP responses at both pre- and post-junctional sites (IC50 = 2.5 µM). Shown to antagonize P2x-purinoceptor-mediated responses in the rabbit urinary bladder. Acts on P2Y, but not on P2U receptors in rat mesenteric arteries. Induces a gradual decline in ATP-activated current to a steady state.
          FormOrange solid
          CAS number192575-19-2
          Chemical formulaC₁₄H₁₀N₃Na₄O₁₂PS₂
          Structure formulaStructure formula
          Purity≥90 by 1H NMR
          SolubilityH₂O (100 mM)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesLi. C. 2000. J. Neurophysiol. 83, 2533.
          Ralevic, V., et al. 1996. Br. J. Pharmacol. 118, 428.