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14-688M | PKG1α Protein, active, 250 µg

14-688M
250 µg  Also available in 10 μg size (cat#14-688) and in bulk (cat#14-688-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-688M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPKG1α Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, full length PKG1α.
      References
      Product Information
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, full length PKG1α. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourcePKG1α, expressed by baculovirus in Sf21 cells.
      Entrez Gene Number
      Gene Symbol
      • PRKG1
      • cGKI-beta
      • FLJ36117
      • PGK
      • PRKGR1A
      • cGKI-alpha
      • cGKI
      • MGC71944
      • OTTHUMP00000061216
      • CGKI
      • PRKG1B
      • cGKI-BETA
      • PRKGR1B
      • DKFZp686K042
      Protein TargetPKG1α
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummarySIZE: 686 amino acids; 77804 Da
      SUBUNIT: Antiparallel homodimer. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1 (By similarity). Interacts with MRVI1.
      DOMAIN: SwissProt: P14619
      SIMILARITY: SwissProt: P14619 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. | Q13976 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain.
      MISCELLANEOUS: Exhibit a substrate specificity similar but not identical to that of CAK.
      Molecular Weight80kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-688) and in bulk (cat#14-688-K).
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-688 PKG1α Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases