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14-927M | PAK1 Protein, active, 250 µg

250 µg  Also available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
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      Replacement Information
      Catalogue Number14-927M
      Trade Name
      • Upstate
      DescriptionPAK1 Protein, active, 250 µg
      OverviewThis protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
      Product Information
      Presentation50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
      ApplicationActive, N-terminal FLAG-tagged, recombinant, human PAK1, amino acids 150-end. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceN-terminal FLAG-tagged, recombinant, human PAK1 amino acids 150-end, expressed by baculovirus in Sf21 insect cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • PAK1
      • Alpha-PAK
      • p21-activated kinase 1
      • PAK-1
      • p65-PAK
      Protein TargetPAK1
      Purification MethodPurified by immunoaffinity chromatography.
      Target Sub-FamilySTE
      UniProt Number
      Molecular Weight46 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of peptide RRRLSFAEPG.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
      Transport Information
      Supplemental Information

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-927 PAK1 Protein, active, 10 µg Show Pricing & Availability

      Product Families


      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases