475914 Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem

475914
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄₇H₇₅NO₁₇ 1400-61-9

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      475914-1GM
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          Glass bottle 1 gm
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          475914-5GM
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              Glass bottle 5 gm
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              Description
              OverviewA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation-selective ionophore that exhibits selectivity for Na+. Increases the activity of Na+ - K+ pump.
              Catalogue Number475914
              Brand Family Calbiochem®
              SynonymsMycostatin
              References
              ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
              Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
              Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
              Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.
              Product Information
              CAS number1400-61-9
              FormOff-white to yellow solid
              Hill FormulaC₄₇H₇₅NO₁₇
              Chemical formulaC₄₇H₇₅NO₁₇
              Structure formula ImageStructure formula Image
              Applications
              ApplicationNystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+.
              Biological Information
              Biological activityPotency: ≥3000 units/mg (anhydrous).
              Purity≥95% by HPLC (sum of two peaks)
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSRF5950000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +2°C to +8°C
              Protect from Light Protect from light
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              475914

              References

              Reference overview
              Gruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
              Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
              Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
              Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.

              Brochure

              Title
              Ionophores Technical Bulletin

              Technical Info

              Title
              EMD Millipore Regulated Product Information
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision10-December-2016 JSW
              SynonymsMycostatin
              DescriptionA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation selective ionophore that exhibits selectivity for Na+. Increases the activity of the Na+-K+ pump. Suggested concentration is 50 µg/ml.
              FormOff-white to yellow solid
              CAS number1400-61-9
              RTECSRF5950000
              Chemical formulaC₄₇H₇₅NO₁₇
              Structure formulaStructure formula
              Purity≥95% by HPLC (sum of two peaks)
              Biological activityPotency: ≥3000 units/mg (anhydrous).
              SolubilityDMSO (50 mg/ml)
              Storage +2°C to +8°C
              Protect from light
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Standard Handling
              Merck USA index14, 6736
              ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
              Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
              Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
              Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.

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              Catalog Number Description  
              475921 Nystatin, Streptomyces noursei, Sterile, Tissue Culture Grade - CAS 1400-61-9 - Calbiochem Show Pricing & Availability

              Categories

              Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores
              Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antifungal Agents