05-23-0310 | Natriuretic Peptide, C-Type, Human and Porcine - CAS 127869-51-6 - Calbiochem

05-23-0310
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₉₃H₁₅₇N₂₇O₂₈S₃ 127869-51-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      05-23-0310-0.5MG
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          Plastic ampoule .5 mg
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          05-23-0310-1MG
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              Plastic ampoule 1 mg
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              Description
              OverviewMember of the natriuretic peptide family that shares structural homology with ANP and plays a role in the regulation of body fluid homeostasis, vascular tone, and vascular growth. Inhibits adenylate cyclase activity in a concentration-dependent manner. Stimulates particulate guanylate cyclase activity. Shown to exert neuromodulatory effects independently of guanylate cyclase activation or adenylate cyclase inhibition.
              Catalogue Number05-23-0310
              Brand Family Calbiochem®
              SynonymsCNP, GLSKGCFGLKLDRIGSMSGLGC
              References
              ReferencesKelley, T., et al. 1997. Am. J. Respir. Cell. Mol. Biol. 16, 464; Inoue, A., et al. 1996. Biochem. Biophys. Res. Commun. 221, 703; Savoie, P., et al. 1995. FEBS Lett. 370, 6; Trachte, G.J., et al. 1995. Am. J. Physiol. 268, C978; Koller, K.J., et al. 1991. Science 252, 120; Sudoh, T., et al. 1990. Biochem. Biophys. Res. Commun. 168, 863.
              Product Information
              CAS number127869-51-6
              ATP CompetitiveN
              FormWhite to off-white lyophilized solid
              FormulationSold on the basis of peptide content.
              Hill FormulaC₉₃H₁₅₇N₂₇O₂₈S₃
              Chemical formulaC₉₃H₁₅₇N₂₇O₂₈S₃
              ReversibleN
              Sold on the basis of peptide contentY
              Applications
              Biological Information
              Primary TargetAdenylate cyclase, particulate guanylate cyclase
              Purity≥96% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceH-Gly-Leu-Ser-Lys-Gly-Cys⁶-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys²²-OH (disulfide bond: 6 → 22)]
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Protect from Moisture Protect from moisture
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              05-23-0310

              References

              Reference overview
              Kelley, T., et al. 1997. Am. J. Respir. Cell. Mol. Biol. 16, 464; Inoue, A., et al. 1996. Biochem. Biophys. Res. Commun. 221, 703; Savoie, P., et al. 1995. FEBS Lett. 370, 6; Trachte, G.J., et al. 1995. Am. J. Physiol. 268, C978; Koller, K.J., et al. 1991. Science 252, 120; Sudoh, T., et al. 1990. Biochem. Biophys. Res. Commun. 168, 863.

              Brochure

              Title
              Nitric Oxide and Oxidative Stress Brochure
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision18-September-2008 RFH
              SynonymsCNP, GLSKGCFGLKLDRIGSMSGLGC
              DescriptionMember of the natriuretic peptide family that shares structural homology with ANP and plays a role in the regulation of body fluid homeostasis, vascular tone and vascular growth. Inhibits adenylate cyclase activity in a concentration-dependent manner. Stimulates particulate guanylate cyclase activity. Shown to exert neuromodulatory effects independent of guanylate cyclase activation or adenylate cyclase inhibition.
              FormWhite to off-white lyophilized solid
              FormulationSold on the basis of peptide content.
              CAS number127869-51-6
              Chemical formulaC₉₃H₁₅₇N₂₇O₂₈S₃
              Peptide SequenceH-Gly-Leu-Ser-Lys-Gly-Cys⁶-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys²²-OH (disulfide bond: 6 → 22)]
              Purity≥96% by HPLC
              Solubility5% acetic acid (1 mg/ml)
              Storage -20°C
              Protect from moisture
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Standard Handling
              ReferencesKelley, T., et al. 1997. Am. J. Respir. Cell. Mol. Biol. 16, 464; Inoue, A., et al. 1996. Biochem. Biophys. Res. Commun. 221, 703; Savoie, P., et al. 1995. FEBS Lett. 370, 6; Trachte, G.J., et al. 1995. Am. J. Physiol. 268, C978; Koller, K.J., et al. 1991. Science 252, 120; Sudoh, T., et al. 1990. Biochem. Biophys. Res. Commun. 168, 863.