AG345 | Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082

AG345
100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information
      Description
      Catalogue NumberAG345
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionNa+/H+ Exchanger-1, Control Peptide for AB3081/AB3082
      OverviewNa+/H+ Exchanger 1 (NHE1) control peptide.
      References
      Product Information
      PresentationLiquid in PBS, pH 7.5.
      Applications
      Key Applications
      • Peptide Inhibition Assay
      Application NotesAntibody blocking (AB3081/AB3082)

      Optimal working concentration must be determined by the end user.
      Biological Information
      Concentration1 mg/mL
      Entrez Gene Number
      Gene Symbol
      • SLC9A1
      • FLJ42224
      • APNH
      • NHE-1
      • Na
      • +H
      • NHE1
      • APNH1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P19634 # Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
      SIZE: 815 amino acids; 90763 Da
      SUBUNIT: Interacts with tescalcin, CHP and CHP2.
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Kidney and intestine.
      PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. & O-glycosylated.
      SIMILARITY: SwissProt: P19634 ## Belongs to the Na(+)/H(+) exchanger (TC 2.A.36.5.1) family.
      MISCELLANEOUS: Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation, the apparent affinity for internal H(+) is increased, resulting in a persistent rise in cytoplasmic pH.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 1999456 1999456
      Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 2005381 2005381
      Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 2037598 2037598

      References

      Reference overviewPub Med ID
      Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.
      H I Rocha-González,G Castañeda-Corral,C I Araiza-Saldaña,M Ambriz-Tututi,N L Caram-Salas,J E Torres-López,J Murbartián,V Granados-Soto
      Neuroscience  160  2009

      Show Abstract
      19248819 19248819

      Data Sheet

      Title
      Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE