A part of MilliporeSigma

GF309 | NT-4 Protein, Human Recombinant Animal Free

10 µg  
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      Key Specifications Table

      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Catalogue NumberGF309
      DescriptionNT-4 Protein, Human Recombinant Animal Free
      Alternate Names
      • NT4
      • Neurotrophin 4
      • Neurotrophin 4/5
      • NT4/5
      Background InformationNeurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
      Product Information
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      ApplicationThe Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityMouse, Rat
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information

      Related Products & Applications

      Product Families


      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors