399250 | NG-Hydroxy-L-arginine, Monoacetate Salt - CAS 53598-01-9 - Calbiochem

399250
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₆H₁₄N₄O₃ · CH₃CO₂H 53598-01-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      399250-5MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Plastic ampoule 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewCell permeable. A key intermediate in the biosynthesis of nitric oxide by constitutive nitric oxide synthase (cNOS). NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450 system. A potent inhibitor of liver and macrophage arginase (Ki = 150 µM).
          Catalogue Number399250
          Brand Family Calbiochem®
          SynonymsNOHA, AcOH
          References
          ReferencesBoucher, J.L., et al. 1994. Biochem. Biophys. Res. Commun. 203, 1614.
          Pufahl, R.A., and Marletta, M.A. 1993. Biochem. Biophys. Res. Commun. 193, 963.
          Boucher, J.L., et al. 1992. Biochem. Biophys. Res. Commun. 187, 880.
          Stuehr, D.J., et al. 1991. J. Biol. Chem. 266, 6259.
          Wallace, G.C., et al. 1991. Biochem. Biophys. Res. Commun. 176, 528.
          Zembowicz, A., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 11172.
          Product Information
          CAS number53598-01-9
          FormWhite solid
          Hill FormulaC₆H₁₄N₄O₃ · CH₃CO₂H
          Chemical formulaC₆H₁₄N₄O₃ · CH₃CO₂H
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetliver and macrophage arginase
          Primary Target K<sub>i</sub>150 µM
          Purity≥98% by elemental analysis
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          399250

          References

          Reference overview
          Boucher, J.L., et al. 1994. Biochem. Biophys. Res. Commun. 203, 1614.
          Pufahl, R.A., and Marletta, M.A. 1993. Biochem. Biophys. Res. Commun. 193, 963.
          Boucher, J.L., et al. 1992. Biochem. Biophys. Res. Commun. 187, 880.
          Stuehr, D.J., et al. 1991. J. Biol. Chem. 266, 6259.
          Wallace, G.C., et al. 1991. Biochem. Biophys. Res. Commun. 176, 528.
          Zembowicz, A., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 11172.

          Brochure

          Title
          Nitric Oxide Donors and Scavengers Technical Bulletin
          Nitric Oxide and Oxidative Stress Brochure
          Pathways and Biomarkers of Oxidative Stress (EMD)
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-June-2008 RFH
          SynonymsNOHA, AcOH
          DescriptionCell-permeable. A key intermediate product in the biosynthesis of nitric oxide from arginine by constitutive nitric oxide synthase (cNOS). Formed by the NADPH-dependent hydroxylation of L-arginine. NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450, providing an alternative biosynthetic route for the production of nitric oxide. A potent inhibitor of liver and macrophage arginase (Ki = 150 µM).
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number53598-01-9
          Chemical formulaC₆H₁₄N₄O₃ · CH₃CO₂H
          Structure formulaStructure formula
          Purity≥98% by elemental analysis
          SolubilityH₂O (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBoucher, J.L., et al. 1994. Biochem. Biophys. Res. Commun. 203, 1614.
          Pufahl, R.A., and Marletta, M.A. 1993. Biochem. Biophys. Res. Commun. 193, 963.
          Boucher, J.L., et al. 1992. Biochem. Biophys. Res. Commun. 187, 880.
          Stuehr, D.J., et al. 1991. J. Biol. Chem. 266, 6259.
          Wallace, G.C., et al. 1991. Biochem. Biophys. Res. Commun. 176, 528.
          Zembowicz, A., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 11172.