480005 | NDSB-201 - CAS 15471-17-7 - Calbiochem

480005
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₈H₁₁NO₃S 15471-17-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      480005-250GM
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          Glass bottle 250 gm
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          480005-25GM
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              Plastic ampoule 25 gm
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              Description
              OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.
              Catalogue Number480005
              Brand Family Calbiochem®
              Synonyms3-(1-Pyridino)-1-propane Sulfonate
              References
              ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
              Vuillard, L., et al. 1995. Biochem. J. 305, 337.
              Product Information
              CAS number15471-17-7
              FormWhite powder
              Hill FormulaC₈H₁₁NO₃S
              Chemical formulaC₈H₁₁NO₃S
              Hygroscopic Hygroscopic
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Purity≥99% by titration
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              R PhraseR: 36/37/38

              Irritating to eyes, respiratory system and skin.
              S PhraseS: 26-36

              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Wear suitable protective clothing.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Irritant
              Storage +15°C to +30°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              480005

              References

              Reference overview
              Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
              Vuillard, L., et al. 1995. Biochem. J. 305, 337.

              Citations

              Title
            • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
            • Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision28-February-2008 JSW
              Synonyms3-(1-Pyridino)-1-propane Sulfonate
              DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
              FormWhite powder
              CAS number15471-17-7
              Chemical formulaC₈H₁₁NO₃S
              Structure formulaStructure formula
              Purity≥99% by titration
              SolubilityH₂O (50 mg/ml)
              Storage +15°C to +30°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
              Toxicity Irritant
              ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
              Vuillard, L., et al. 1995. Biochem. J. 305, 337.
              Citation
            • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
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              Categories

              Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines