495417 | N-Oleoyl Ethanolamine - CAS 111-58-0 - Calbiochem

495417
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₃₉NO₂ 111-58-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      495417-25MG
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          Plastic ampoule 25 mg
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          Description
          OverviewA potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
          Catalogue Number495417
          Brand Family Calbiochem®
          SynonymsN-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
          References
          ReferencesPahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
          Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
          Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.
          Product Information
          CAS number111-58-0
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₀H₃₉NO₂
          Chemical formulaC₂₀H₃₉NO₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetAcid ceramidase
          Primary Target IC<sub>50</sub>~ 500 µM against acid ceramidase
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          495417

          References

          Reference overview
          Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
          Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
          Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-August-2008 RFH
          SynonymsN-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
          DescriptionA potent inhibitor of the ceramidase found in human kidney and cerebellum. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
          FormWhite solid
          CAS number111-58-0
          Chemical formulaC₂₀H₃₉NO₂
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityEthanol (5 mg/ml), Chloroform (5 mg/ml), or Methanol (5 mg/ml)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesPahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
          Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
          Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.