FCMAB246A4 | Milli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182) Antibody, Alexa Fluor® 488, clone 28B10

100 tests  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H FC M AlexaFluor®488 Monoclonal Antibody
      Catalogue NumberFCMAB246A4
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182) Antibody, Alexa Fluor® 488, clone 28B10
      Background InformationThe p38 family refers to the SAPK2/3 Kinases (Stess-Activated Protein Kinases), a subfamily of JNK/SAPK family. p38/SAPK Kinases are also activated by stresses, most notably inflammatory cytokines, irradiation, and certain toxins such as anisomycin and arsenite. SAPKs have been implicated in many pathological conditions, including inflammation, cancer and neurodegenerative diseases. As with the other MAPK family members (ERK, JNK, p38MAPK, and ERK5), p38 is activated through phosphorylation on both threonine and tyrosine residues at the Thr-X-Tyr dual phosphorylation motif, where X is Gly for p38. Once phosphorylated and active, it then goes on to phosphorylate downstream targets in both the cytoplasm and the nucleus. Some of their main targets of p38 are the kinase MAPKAPK2 and the transcription factor ATF2 that are activated via their phosphorylation.
      Product Information
      ApplicationThis Milli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182) Antibody is validated for use in Flow Cytometry for the detection of phospho-p38 MAPK (Thr180/Tyr182).
      Key Applications
      • Flow Cytometry
      Biological Information
      Cloneclone 28B10
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-phospho-p38 MAPK (Thr180/Tyr182), Alexa Fluor#174; 488, clone 28B10 - NRG1786456 NRG1786456
      Milli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182), Alexa Fluor® 488, clone 28B10 -2529367 2529367
      Milli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182), Alexa Fluor® 488, clone 28B10- 2830169 2830169
      Milli-Mark™ Anti-phospho-p38 MAPK (Thr180/Tyr182), Alexa Fluor® 488, clone 28B10 - 2341022 2341022

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      Life Science Research > Antibodies and Assays > Primary Antibodies