A part of MilliporeSigma

FCMAB135F | Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

100 tests  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H FC M FITC Monoclonal Antibody
      Catalogue NumberFCMAB135F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark Anti-BMP-7-FITC Antibody, clone 2A10
      Alternate Names
      • Bone morphogenetic protein-7
      • osteogenic protein-1
      Background InformationBone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
      Product Information
      • HeLa cells.
      PresentationPurified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      ApplicationDetect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Working Solution Cells / test Total Reaction Volume
      5 μl 5 x 105 Cells / 95 μl PBS 100 μl
      10 μl 1 x 106 Cells / 90 μl PBS 100 μl
      Biological Information
      Immunogen Recombinant full-length BMP-7 protein.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis monoclonal antibody recognizes BMP-7.
      Species Reactivity
      • Human
      Species Reactivity NoteTested and passed on Human. Unconjugated antibody (MAB4350) also reacts against Mouse.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • BMP7
      • OP1
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFunction Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

      Subunit structure Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1 By similarity.

      Subcellular location Secreted.

      Tissue specificity Expressed in the kidneys and bladder. Lower levels seen in the brain.

      Post-translational modification Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (Ref.5).

      Pharmaceutical use Available under the names Osigraft (Stryker). Its use is indicated in the treatment of tibial non-union of at least 9 month duration, secondary to trauma, in skeletally mature patients, in cases where autograft has failed or is unfeasible.

      Sequence similarities Belongs to the TGF-beta family.
      Molecular Weight 46kDa Observed
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using HeLa cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-BMP-7-FITC, clone 2A10 - 2067779 2067779
      Milli-Mark Anti-BMP-7-FITC, clone 2A10 - 1959240 1959240
      Milli-Mark Anti-BMP-7-FITC, clone 2A10 - 2207208 2207208
      Milli-Mark Anti-BMP-7-FITC, clone 2A10 - NG1875695 NG1875695
      Milli-Mark Anti-BMP-7-FITC, clone 2A10 - NRG1724874 NRG1724874
      Milli-Mark™ Anti-BMP-7-FITC, -2776279 2776279
      Milli-Mark™ Anti-BMP-7-FITC, -2782656 2782656
      Milli-Mark™ Anti-BMP-7-FITC, -2801954 2801954
      Milli-Mark™ Anti-BMP-7-FITC, -2804293 2804293
      Milli-Mark™ Anti-BMP-7-FITC, clone 2A10 - 2562460 2562460
      Milli-Mark™ Anti-BMP-7-FITC, clone 2A10 -2705073 2705073
      Milli-Mark™ Anti-BMP-7-FITC, clone 2A10 - 2399475 2399475


      Benchtop Flow Cytometry Solutions Kits and Reagents
      Innovative Solutions for Flow Cytometry Analysis (EMD)

      Related Products & Applications

      Related Products

      Catalog Number Description  
      MAB4350 Anti-BMP-7 Antibody, clone 2A10 Show Pricing & Availability
      MAB4429 Anti-BMP-7 (Pro-peptide) Antibody, clone 2 Show Pricing & Availability


      Catalog Number Description  
      MAB4350 Anti-BMP-7 Antibody, clone 2A10 Show Pricing & Availability

      Product Families

      Related Products By: Brand Facete

      View Gene Related Products for this Target


      Life Science Research > Antibodies and Assays > Primary Antibodies