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FCMAB245P | Milli-Mark™ Anti-mouse Interleukin-4-PE Antibody, clone 11B11

100 tests  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M FC R Phycoerythrin Monoclonal Antibody
      Catalogue NumberFCMAB245P
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-mouse Interleukin-4-PE Antibody, clone 11B11
      Alternate Names
      • B cell growth factor 1
      • B-cell stimulatory factor 1
      • B_cell stimulatory factor 1
      • Lymphocyte stimulatory factor 1
      • interleukin 4
      Background InformationInterleukin-4 (IL-4) is a cytokine that stimulates activated B-cell and T-cell proliferation and induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. These Th2 cells, in turn, also produce IL-4. IL-4 also acts as a key regulator in humoral and adaptive immunity and induces B-cell class switching to IgE, as well as up-regulating MHC class II production. Mutations in the IL-4 gene may lead to a susceptibility to ischemic stroke or cerebral infarction. Overproduction of IL-4 is associated with allergies.
      Product Information
      • Mick2 cells
      PresentationPurified rat monoclonal IgG1κ conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
      ApplicationMilli-Mark Anti-mouse Interleukin-4-PE Antibody, clone 11B11 detects level of mouse Interleukin-4 & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse IL-4.
      SpecificityAntibody recognizes IL-4.
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • IL4
      • Binetrakin
      • Pitrakinra
      • BSF1
      • BSF-1
      • IL-4
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.


      SEQUENCE SIMILARITIES: Belongs to the IL-4/IL-13 family.
      Molecular Weight 15 kDa Calculated
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Mick2 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies