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FCMAB136F | Milli-Mark™ Anti-DPPA-2-FITC Antibody, clone 6C1.2

FCMAB136F
100 tests  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M FC M FITC Monoclonal Antibody
      Description
      Catalogue NumberFCMAB136F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-DPPA-2-FITC Antibody, clone 6C1.2
      Alternate Names
      • Pluripotent embryonic stem cell-related gene 1 protein
      • Developmental pluripotency associated 2
      Background InformationDPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
      References
      Product Information
      FormatFITC
      Control
      • Mouse ESC (CMTI-2)
      PresentationPurified mouse monoclonal IgG2a in buffer containing PBS, 15mg/mL BSA with 0.1% sodium azide.
      Applications
      ApplicationMilli-Mark Anti-DPPA-2-FITC Antibody, clone 6C1.2 detects level of DPPA-2 & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenFull length recombinant mouse DPPA-2 protein
      Clone6C1.2
      HostMouse
      SpecificityAntibody recognizes DPPA-2 antigen.
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PESCRG1
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: May play a role in maintaining cell pluripotentiality.

      SUBCELLULAR LOCATION: Nucleus.

      TISSUE SPECIFICITY: Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.

      SEQUENCE SIMILARITIES: Contains 1 SAP domain.
      Molecular Weight 34 kDa Calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Mouse ESC (CMTI-2)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies