474705 | Mevastatin, Sodium Salt - Calbiochem

474705
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₂₃H₃₅O₆ · Na

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      474705-5MG
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      Stocked 
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          Plastic ampoule 5 mg
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          Description
          OverviewCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays.
          Catalogue Number474705
          Brand Family Calbiochem®
          References
          ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
          Endo, A. 1992. J. Lipid Res. 33, 1569.
          Product Information
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₃H₃₅O₆ · Na
          Chemical formulaC₂₃H₃₅O₆ · Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetHMG-CoA reductase
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          474705

          References

          Reference overview
          Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
          Endo, A. 1992. J. Lipid Res. 33, 1569.

          Brochure

          Title
          Biologics 32.4 ( 1.19 MB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision08-August-2008 RFH
          DescriptionCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G1 phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₂₃H₃₅O₆ · Na
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityDMSO (30 mg/ml) or Ethanol (20 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
          Endo, A. 1992. J. Lipid Res. 33, 1569.