454565 | Methyl Arachidonyl Fluorophosphonate - Calbiochem

454565
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₂₁H₃₆FO₂P

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      454565-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewA selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not of secretory PLA2.
          Catalogue Number454565
          Brand Family Calbiochem®
          SynonymsMAFP, cPLA2α Inhibitor III
          References
          ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
          Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
          Product Information
          ATP CompetitiveN
          FormLiquid
          FormulationIn methyl acetate.
          Hill FormulaC₂₁H₃₆FO₂P
          Chemical formulaC₂₁H₃₆FO₂P
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetcalcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          454565

          References

          Reference overview
          Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
          Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-August-2008 RFH
          SynonymsMAFP, cPLA2α Inhibitor III
          DescriptionA selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not secretory PLA2.
          FormLiquid
          FormulationIn methyl acetate.
          Chemical formulaC₂₁H₃₆FO₂P
          Structure formulaStructure formula
          Purity≥98% by TLC
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
          Toxicity Standard Handling
          ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
          Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.