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444225 | MMP-3 Inhibitor II - CAS 161314-17-6 - Calbiochem

444225
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₃H₂₀N₂O₅S 161314-17-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      444225-5MG
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          Glass bottle 5 mg
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          Description
          OverviewA potent and cell-permeable inhibitor of human MMP-3 (Ki = 130 nM).
          Catalogue Number444225
          Brand Family Calbiochem®
          SynonymsN-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
          References
          ReferencesKato, N., et al. 2002. Genome Informatics 13, 272.
          MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
          Product Information
          CAS number161314-17-6
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₃H₂₀N₂O₅S
          Chemical formulaC₁₃H₂₀N₂O₅S
          ReversibleN
          Structure formula Image
          Applications
          Biological Information
          Primary Targethuman MMP-3
          Primary Target K<sub>i</sub>130 nM against human MMP-3
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          444225

          References

          Reference overview
          Kato, N., et al. 2002. Genome Informatics 13, 272.
          MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-April-2011 RFH
          SynonymsN-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
          DescriptionA cell-permeable, potent inhibitor of human MMP-3 (stromelysin; Ki = 130 nM).
          FormWhite solid
          CAS number161314-17-6
          Chemical formulaC₁₃H₂₀N₂O₅S
          Structure formula
          Purity≥98% by TLC
          SolubilityDMSO (30 mg/ml) or Ethanol (8 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesKato, N., et al. 2002. Genome Informatics 13, 272.
          MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

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          Catalog Number Description  
          444218 MMP-3 Inhibitor I - Calbiochem Show Pricing & Availability

          Categories

          Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Matrix Metalloproteinase (MMP) Inhibitors