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14-690M | MLK1 Protein, active, 250 µg

250 µg  Also available in 10 μg size (cat#14-690) and in bulk (cat#14-690-K).
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      Replacement Information
      Catalogue Number14-690M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionMLK1 Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, human MLK1, amino acids 134-414
      Product Information
      ApplicationActive, N-terminal 6His-tagged, recombinant, human MLK1, amino acids 134-414, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Entrez Gene Number
      Gene Symbol
      • MAP3K9
      • MLK1
      • PRKE1
      Protein TargetMLK1
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTKL
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P80192 # Activates the JUN N-terminal pathway.
      COFACTOR: Magnesium.
      SIZE: 1104 amino acids; 121895 Da
      SUBUNIT: Homodimer (By similarity).
      TISSUE SPECIFICITY: Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.
      PTM: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.
      SIMILARITY: SwissProt: P80192 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. & Contains 1 protein kinase domain. & Contains 1 SH3 domain.
      Molecular Weight35.3kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of Casein
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-690) and in bulk (cat#14-690-K).
      Transport Information
      Supplemental Information


      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-690 MLK1 Protein, active, 10 µg Show Pricing & Availability

      Product Families


      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases