RKTX2MAG-37K MILLIPLEX MAP Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay

RKTX2MAG-37K
Design And Price Your Kit

Overview

Replacement Information

Key Specifications Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
Alpha-1 Acid Glycoprotein (AGP), Albumin, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL R Mplex Luminex xMAP
Description
Catalogue NumberRKTX2MAG-37K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay
Background InformationMILLIPLEX® MAP Rat Kidney Toxicity Magnetic Bead Panels 1 & 2, coupled with the Luminex® xMAP® platform in a magnetic bead format, enables you to focus on discovery so you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, dramatically improving productivity.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Inter-assay: AGP < 20%
    All other analytes < 15%
  • Intra-assay: AGP < 15%
    All other analytes < 10%
Panel TypeMAGNETIC Toxicity
Applications
ApplicationThe analytes available for this multiplex kit are: Albumin, AGP, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL.
Key Applications
  • Multiplexing
Application Notes• This is an overnight assay.
• This assay requires 25 μL of 1:500 diluted urine sample per well.
Biological Information
SpecificityThere was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Species Reactivity
  • Rat
Analytes Available
  • Alpha-1 Acid Glycoprotein (AGP)
  • Albumin
  • ß2M
  • Cystatin C
  • EGF
  • Lipocalin-2/NGAL
Assay PanelEverything you need in a single kit.
Accuracy
  • 70% - 123%
Physicochemical Information
Sensitivity
  • See kit protocol for individual analytes sensitivities.
Standard Curve Range
  • Albumin: 10.97 – 8,000 ng/mL
  • AGP: 1.37 – 1,000 ng/mL
  • β2M: 0.48 – 350 ng/mL
  • Cystatin C: 0.01 – 8 ng/mL
  • EGF: 0.00 – 2 ng/mL
  • Lipocalin-2/NGAL: 0.01 – 10 ng/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

Documentation

Protocols

Title
Protocol: Rat Kidney Toxicity Magnetic Bead Panel 2

MILLIPLEX MAP Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay SDS

Title

Safety Data Sheet (SDS) 

References

Reference overviewPub Med ID
Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers.
Wunnapuk, K; Gobe, G; Endre, Z; Peake, P; Grice, JE; Roberts, MS; Buckley, NA; Liu, X
Toxicology letters  225  192-200  2014

Show Abstract
24361898 24361898
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology letters  225  467-78  2014

Show Abstract
24480514 24480514

Brochure

Title
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions (SigmaMillipore)
Analyte Quarterly Vol 1 2019
Protein Detection Platform and Services Brochure
The Power of Biomarker Analysis

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Ranges - Milliplex Rat Kidney Toxicity Magnetic Bead Panel 2
White Paper: Detection of vancomycin-induced subacute nephrotoxicity using MILLIPLEX® map rat kidney toxicity multiplex panels

Data Sheet

Title
Full Service Custom-built Assays

Posters

Title
Toxicology in drug discovery and development: Biomarkers and model organisms (EMD)