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AG201 | MCT4, control peptide for AB3550P

AG201
100 µg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberAG201
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionMCT4, control peptide for AB3550P
      OverviewA 19 amino acid peptide sequence within the cytoplasmic domain of human MCT4 (1).
      References
      Product Information
      PresentationLiquid in PBS containing 0.1% BSA and 0.1% sodium azide.
      Applications
      Key Applications
      • Cell Function Assay
      Application NotesFor use in blocking the reactivity of AB3550P.

      Optimal working dilution must be determined by the end user.
      Biological Information
      Concentration1 mg/mL
      Entrez Gene Number
      Entrez Gene SummaryLactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM]
      Gene Symbol
      • SLC16A3
      • MCT3
      • MGC138472
      • MGC138474
      • MCT4
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O15427 # Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
      SIZE: 465 amino acids; 49469 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Highly expressed in skeletal muscle.
      SIMILARITY: SwissProt: O15427 ## Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MONOCARBOXYLATE TRANSPORTER 5 -2761529 2761529
      MONOCARBOXYLATE TRANSPORTER 5 CONTROL PEPTIDE - 2109544 2109544

      References

      Reference overviewPub Med ID
      The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation.
      Halestrap, A P and Price, N T
      Biochem. J., 343 Pt 2: 281-99 (1999) 1999

      Show Abstract
      10510291 10510291

      Data Sheet

      Title
      MCT4, control peptide for AB3550P - Data Sheet