434692 | Leukotriene C₄ - CAS 72025-60-6 - Calbiochem

434692
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₀H₄₇N₃O₉S 72025-60-6

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      434692-50UG
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          Alu drum 50 μg
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          Description
          Overview

          This product has been discontinued.



          Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.

          Catalogue Number434692
          Brand Family Calbiochem®
          SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
          References
          ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
          Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.
          Product Information
          CAS number72025-60-6
          ATP CompetitiveN
          FormLiquid
          FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
          Hill FormulaC₃₀H₄₇N₃O₉S
          Chemical formulaC₃₀H₄₇N₃O₉S
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetMicrosomal glutathione transferase-1
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSMB9143500
          Safety Information
          R PhraseR: 11-23/24/25-39/23/24/25

          Highly flammable.
          Toxic by inhalation, in contact with skin and if swallowed.
          Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
          S PhraseS: 16-7-36/37-45

          Keep away from sources of ignition - No Smoking.
          Keep container tightly closed.
          Wear suitable protective clothing and gloves.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Flammable
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          434692

          References

          Reference overview
          Bannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
          Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.

          Brochure

          Title
          Bioactive Lipids Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-May-2008 RFH
          SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
          DescriptionImplicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.
          FormLiquid
          FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
          CAS number72025-60-6
          RTECSMB9143500
          Chemical formulaC₃₀H₄₇N₃O₉S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
          Toxicity Flammable
          Merck USA index14, 5455
          ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
          Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.