428020 | Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem

428020
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₂₉NO₅S 76343-94-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      428020-1MG
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          Plastic ampoule 1 mg
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          428020-5MG
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              Description
              OverviewA structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes; 10 to 100-fold more potent than cytochalasins.
              Catalogue Number428020
              Brand Family Calbiochem®
              References
              ReferencesSpector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
              de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
              Coue, M., et al. 1987. FEBS Lett. 213, 316.
              Spector, I., et al. 1983. Science 219, 493.
              Product Information
              CAS number76343-94-7
              ATP CompetitiveN
              FormOff-white to yellow solid
              Hill FormulaC₂₀H₂₉NO₅S
              Chemical formulaC₂₀H₂₉NO₅S
              ReversibleN
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Primary TargetActin polymerization
              Purity≥95% by HPLC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              R PhraseR: 20/21/22

              Harmful by inhalation, in contact with skin and if swallowed.
              S PhraseS: 36

              Wear suitable protective clothing.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Harmful
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              428020

              References

              Reference overview
              Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
              de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
              Coue, M., et al. 1987. FEBS Lett. 213, 316.
              Spector, I., et al. 1983. Science 219, 493.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision20-January-2011 JSW
              DescriptionA structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes. 10 to 100-fold more potent than cytochalasins.
              FormOff-white to yellow solid
              CAS number76343-94-7
              Chemical formulaC₂₀H₂₉NO₅S
              Structure formulaStructure formula
              Purity≥95% by HPLC
              SolubilityDMSO (25 mg/ml), Methanol (50 mg/ml),or Ethanol (25 mg/ml)
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
              Toxicity Harmful
              Merck USA index14, 5378
              ReferencesSpector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127.
              de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825.
              Coue, M., et al. 1987. FEBS Lett. 213, 316.
              Spector, I., et al. 1983. Science 219, 493.