437600 | LPD-12

437600
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₃₁H₂₂₄N₃₂O₃₇

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      437600-1MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Plastic ampoule 1 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewA water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM; micelle MW ~ 23,100; aggregation number ~ 8.1; partial specific volume ~ 0.77 cm3/g). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.
          Catalogue Number437600
          Brand Family Calbiochem®
          SynonymsLipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂
          References
          ReferencesMcGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.
          Product Information
          CMC< 1 μM
          FormWhite lyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₃₁H₂₂₄N₃₂O₃₇
          Chemical formulaC₁₃₁H₂₂₄N₃₂O₃₇
          Hygroscopic Hygroscopic
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Peptide SequenceAc-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          437600

          References

          Reference overview
          McGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.

          Brochure

          Title
          Biological Detergents Brochure
          Detergents Booklet
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-August-2008 RFH
          SynonymsLipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂
          DescriptionA water soluble, amphiphilic α-helical, non-denaturing lipopeptide detergent (LPD) that forms small micelles (CMC <1 µM; micelle MW ~23,100; aggregation number ~8.1; partial specific volume ~0.77 cm3/g) and effectively mimics lipid bilayers. Shown to solubilize as well as stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~250 µM and [protein] ~22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.
          FormWhite lyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₃₁H₂₂₄N₃₂O₃₇
          Peptide SequenceAc-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂
          Purity≥95% by HPLC
          SolubilityH₂O (100 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Irritant
          ReferencesMcGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.