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14-620M | LMPTP-B Protein, 250 µg

250 µg  Also available in 10 μg size (cat#14-620) and in bulk (cat#14-620-K).
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      Replacement Information
      Catalogue Number14-620M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionLMPTP-B Protein, 250 µg
      OverviewGST-tagged, recombinant, full length, human LMPTP-B
      Product Information
      ApplicationGST-tagged, recombinant, full length, human LMPTP-B, for use in Phosphatase Assays.
      Key Applications
      • Phosphatase Assay
      Biological Information
      SourceExpressed in E. coli
      Entrez Gene Number
      Entrez Gene SummaryThe product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene.
      Gene Symbol
      • ACP1
      • HAAP
      • LMW-PTP
      • LMW-PTPase
      • MGC3499
      • MGC111030
      Protein TargetLMPTP-B
      Purification MethodGlutathione agarose affinity chromatography
      Target Sub-FamilyTyr phosphatase
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P24666 # Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
      SIZE: 158 amino acids; 18042 Da
      SUBUNIT: Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3.
      TISSUE SPECIFICITY: T-lymphocytes express only isoform 2.
      SIMILARITY: SwissProt: P24666 ## Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
      Molecular Weight44.4kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by dephosphorylation of DiFMUP
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-620) and in bulk (cat#14-620-K).
      Transport Information
      Supplemental Information