420411 | Kanamycin Sulfate, Streptomyces kanamyceticus, Cell Culture-Tested - CAS 25389-94-0 - Calbiochem

420411
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₈H₃₆N₄O₁₁ · H₂SO₄ 25389-94-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      420411-25GM
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          Glass bottle 25 gm
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          420411-5GM
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              Glass bottle 5 gm
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              Description
              OverviewAn aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
              Recommended working concentration: 100 µg/ml.
              Contains >98% kanamycin A. Potency: ≥750 µg/mg
              Catalogue Number420411
              Brand Family Calbiochem®
              References
              ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Cardon, G.H., et al. 1993. Plant J. 3, 773.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
              Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
              Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
              Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
              Product Information
              CAS number25389-94-0
              FormWhite to off-white solid
              Hill FormulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
              Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
              Applications
              Biological Information
              Primary Targetprotein biosynthesis that acts on the 30S ribosome
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSNZ3225030
              Safety Information
              R PhraseR: 36/37/38-42/43-60-61

              Irritating to eyes, respiratory system and skin.
              May cause sensitization by inhalation and skin contact.
              May impair fertility.
              May cause harm to the unborn child.
              S PhraseS: 26-36/37/39-45

              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Wear suitable protective clothing, gloves and eye/face protection.
              In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Carcinogenic / Teratogenic
              Storage +15°C to +30°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              420411

              References

              Reference overview
              Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Cardon, G.H., et al. 1993. Plant J. 3, 773.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
              Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
              Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
              Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

              Brochure

              Title
              Antibiotics Profiler
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision24-September-2010 JSW
              DescriptionAn aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity. Useful for the selection of kanamycin resistant plasmids in E. coli. Tested and found to be negative for cytotoxicity against HeLa cells. Contains more than 98% kanamycin A.
              FormWhite to off-white solid
              CAS number25389-94-0
              RTECSNZ3225030
              Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
              SolubilityH₂O (10 mg/ml)
              Storage +15°C to +30°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Toxicity Carcinogenic / Teratogenic
              Merck USA index14, 5281
              ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Cardon, G.H., et al. 1993. Plant J. 3, 773.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
              Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
              Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
              Umezawa, S., et al. 1968. J. Antibiot. 21, 367.